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Sell Ivermectin Injection

Sell Ivermectin Injection
Categories Plastic Processing Machinery
Delivery Time: within 5 working days(depends on your quantity)
Sample Price: Depending on the quality demanded
Place of Origin: china
Category: Plastic Injection Machinery
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Sell Ivermectin Injection


Ivermectin Injection

Main component: Sterile solution mixed by ivermectin and eligible solvent

Description: Colorless, clear liquid,a little sticky.

Pharmacologic action:

PharmacodynamicsIt has favorable killing effect to endoparasite and ectoparasite especially arthropod and endoparasite. The mechanism of action is promote Presynaptic Neuronal to releaseγaminobutyric acidGABA,thereby open chloride channel mediated by GABA, thus open the chloride channel mediated by GABA . also has selectivity and high affinity to the chloride channel mediated by glutamic acid which is nearby mediated point of GABA of the invertebrate nerves and muscles cell. Chlorine ion current can reduce membrane impedance of cell, result in slight depolarization of postsynaptic cell prohibition , interfere the signal transmission between nerve and muscle, so that the polypide become lack and paralysis, then die or be eliminated. Consistency integrator cell and excitatory neuron is the site of action to edlworm, while Neuromuscular Junctions is the site of action to arthropod.

Pharmacokinetics The bioavailability is high by Subcutaneous injection, can be distributed in majority tissue, but not easily enter cerebrospinal fluid. Apparent volumes of distribution of cattle, sheep, pig, dog respectively are 0.452.44.64 and 2.4l/kg. The have long half life in majority animals. In cattle, sheep, pig, dog are respectively 23270.5 and 2 days. Its metabolized in liver. the method is hydroxylation in sheep and methylation in swine. It be eliminated by excrement. less than 5% of it is eliminated by urine in original appearance or metabolic product. For lactating animals, even 5% of it be eliminated from galact.

Drug interaction: If used together with Carbilazine, there will lead to severe or fatal cerebropathy.

Application: Prevent and cure nemathelminthiasis of gastrointestinal tract, buffalo-hide rope warble fly larvina, psoroptosis of sheep , gaile of pig and other parasitosis.

Usage and dosage: Subcutaneous injectionpro dosi, cattlesheep 0.2mg /kg b.w.pig 0.3mg /kg b.w.

Adverse effect:

24 hours after medication, the horse may appear dropsy and pruritus nearby medioventral line because of allergic response caused by the dead of filariae. And the dropsy will decrease in 7-10 days, the pruritus will relieve within 3 weeks.

When using for treat babiche larvae disease of cattle, if the larvae died in criticality part, it will cause severe adverse effect. If in spinal canal, will cause palsy and stagger; if in oesophagus, will cause dribble or gaseous. If treat immediately after the warble fly season or after migratory stage of warble fly larval, the above problems will be avoided. Meanwhile, the injection site will be indisposition or edema fugax, this will decrease by injecting at different site(the dosage no more than 10ml at each site).

When treating microfilaria infect, dog may have shock response, this maybe related to the dead microfilaria.

Poultry may die, hypnody or decrease food appetite.

Announcement:

1Only hypodermic injection is permitted,intramuscular injection, intravenous injection will cause toxic reaction,the dosage of each hypodermic injection should be limited in 10ml.

2Ivermectin Injection which contains glycerine mini-formaldehyde and propylene glycol, only refer to cattle, sheep, pig and reindeer,if used to other animals especially for dog and horse, it will cause serious local reaction.

3Various dogs are safety in using it, while shepherd dog is sensitive to it,dosage above 0.1mg/kg will lead to serious adverse effect,should be careful in this.

4It has rank poison to prawn, fish and aquatic,package which remaining this dug shouldnt contaminate water source.

Withdraw period: Cowsheep 35 days,pig 28 days,prohibited during lactation period

Specification: 5ml0.05g

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