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Sell High Quality 99% Purity Veterinary Grade Ivermectin Raw Powder CAS:70288-86-7

Categories Pharmaceutical Raw Materials
Brand Name: Kafen
Model Number: 70288-86-7
Certification: GMP
Place of Origin: China
MOQ: 10g
Price: Negotiable
Payment Terms: Western Union, MoneyGram,Bitcoin and Bank Transfer
Supply Ability: 5000KG/Month
Delivery Time: Within 24 hours after receiving your payment
Packaging Details: As you request
CAS: 70288-86-7
EINECS: 274-536-0
MF: C48H74O14
MW: 875.09
Storage Temparature: 2-8°C
Purity: 99%
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Sell High Quality 99% Purity Veterinary Grade Ivermectin Raw Powder CAS:70288-86-7

Ivermectin
CAS No: 70288-86-7
EINECS No: 274-536-0
Molecular Formular: C95H146O28
Molecular Weight: 1736.16
Appearance: White powder
Recommended dosage: 0.1%-3%


Product nameIvermectin
Other nameivermform; Mk933; 22, 23 - dihydroavermectin B1; Uvemec; Ivosint; Ivermectin. EQVALEN; IVOMEC;
CAS no70288-86-7
Molecular formulaC48H74O14
Molecular weight875.09300
Propertieswhite crystalline powder; Tasteless. This product is soluble in methanol, ethanol, acetone and ethyl acetate. It is almost insoluble in water, and is slightly wettable.
Storage conditions2-8
Purposeivermectin is widely used in cattle, sheep, horses, pigs, gastrointestinal nematodes, lung nematodes and parasitic arthropod, canine intestinal nematodes, ear mites, scabies mites, heart silk worm and microfilariae, gastrointestinal nematodes and external parasites and poultry.

Description:
Ivermectin, as antibiotics, nematodes, insects and mites are killed drive activity, made with ivermectin injections, tablets for the treatment of gastrointestinal nematodes of livestock, leather maggots, maggots grain leather, sheep nasal bot and pigs, sheep scabies.In addition, ivermectin can be used for the treatment of poultry parasitic nematodes (such as roundworms, lung nematodes, etc.).Can also be made agricultural insecticide, miticide, widely used to kill parasitic mites on plants, diamondback moth, cabbage worm, leafminers, psylla, nematodes and the like.


Application

Ivermectin is widely used in cattle, sheep, horses, pigs, gastrointestinal nematodes, lung nematodes and parasitic arthropod, canine intestinal nematodes, ear mites, scabies mites, silk worm and microfilariae, gastrointestinal nematodes and external parasites and poultry. This product belong to the broad-spectrum drug resistant parasites.

Ivermectin for a variety of most of the life cycle of nematodes (but not all nematodes) role; For dish tail filarial microfilariae effectively, but for adult worms; For only in intestinal fecal round worms are also effective.

Ivermectin has the selective inhibitory effect, with no spinal nerve cells and muscle cells in the animal glutamic acid chlorine ion channels of the valve is the high binding affinity, leading to the proliferation of the chloride ion permeability of cell membrane, cause nerve cells or muscle cells hyperpolarization, parasites paralysis or death


Function:


1.Ivermectin is used in veterinary medicine.It is sometimes administered in combination with other medications to treat a broad spectrum of animal parasites.Some dog breeds (especially the Rough Collie, the Smooth Collie, the Shetland Sheepdog, and the Australian Shepherd), though, have a high incidence of a certain mutation within the MDR1 gene (coding for P-glycoprotein);Affected animals are particularly sensitive to the toxic effects of ivermectin.

2.Ivermectin is sometimes used as an acaricide in reptiles, both by injection and as a diluted spray.While this works well in some cases, care must be taken, as several species of reptiles are very sensitive to ivermectin.Use in turtles is particularly contraindicated.

3.It is mainly used in humans in the treatment of onchocerciasis (river blindness), but is also effective against other worm infestations (such as strongyloidiasis, ascariasis, trichuriasis, filariasis and enterobiasis), and some epidermal parasitic skin diseases, including scabies.

4.Ivermectin, under the brand name Mectizan, is currently being used to help eliminate river blindness (onchocerciasis) in the Americas, and to stop transmission of lymphatic filariasis and onchocerciasis around the world.Currently, large amounts of ivermectin are donated by Merck to fight river blindness in countries unable to afford the drug.The disease is endemic in 30 African countries, six Latin American countries, and Yemen, according to studies conducted by the World Health Organization.The drug rapidly kills microfilariae, but not the adult worms.A single oral dose of ivermectin, taken annually for the 10- to 15-year lifespan of the adult worms, is all that is needed to protect the individual from onchocerciasis.


COA:

Test itemSpecifications
DescriptionA white or yellowish-white crystalline powder
IdentificationIR.HPLC
Appearance of solutionClear and not ore intensely colored than reference solution BY7
Specific optical rotation-17--20°
Impurity with a relative retention of 1.3 to 1.5≤2.5%
Any other impurity(apart from the 2 rincipal peaks)≤1.0%
The sum of all related sub.≤5.0%
Limit of ethanol≤5.0%
Limit of formamide≤3.0%
Heavy metals≤20ppm
Water≤1.0%
Sulphated ash≤0.1%
Assay(HPLC, base on drying)H2Bla/(H2Bla+H2BLB)≥90.0%
102.0%)≥(H2Bla+H2Bla) )≥95.0%
Notice: the assay of Bl and Bla calculated on the moisture, ethanol and formamid free bases

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