Recombinant Trypsin Inhibitor, Expressed in E.coli, Competitive Serine Protease Inhibitor

Recombinant Trypsin Inhibitor, Expressed in E.coli, Competitive Serine Protease Inhibitor

Recombinant Aprotinin

Anonym: Trypsin Inhibitor

CAS: 9087-70-1

Source: Expressed in E. Coli

Description

Aprotinin is a competitive serine protease inhibitor that inhibits trypsin, chymotrypsin, kallikrein and plasmin. Aprotinin forms stable complexes with and blocks the active sites of enzymes. Binding is reversible with most aprotinin-protease complexes and dissociating at pH >10 or <3. Effective concentration is equimolar with protease.

Recombinant Animal Components Free

Recombinant aprotinin is expressed in E. Coli, and purified by HPLC. It contains no animal-derived components. This is a recombinant form of bovine lung aprotinin, which is traditionally isolated from bovine lung by methods involving fractional precipitation, gel filtration, and ion exchange chromatography.

      Shanghai Yaxin Biotechnology Co., Ltd. was founded in 2008, which is a high-tech enterprise that focuses on researching and producing the recombinant proteins.YaxinBio is the first and only company on researching and producing the recombinant carboxypeptidase B and recombinant trypsin. Animal-origin-free enzymes are specially used in the human recombinant insulin production, and exporting abroad.

       Recombinant trypsin is used in the cell culturing process,which conforms to the 2014 USP on the usage of trypsin in the cell culture and the 2020 CP. Animal-origin-free is very important for the production of antibody and vaccine.Usage of recombinat trypsin fundamentally solves the problem of animal original virus contamination in the human recombinant insulin production.

       YaxinBio insists on “scientific and technological innovation”, has developed with independent intellectual property rights of the products.YaxinBio obtained the support of Chinese ministry of science and technology and Shanghai innovation fund project in 2010; The products recombinant trypsin, recombinant carboxypeptidase B and recombinant protein A won the Shanghai high-tech achievement transformation project in Sep.2013.

        Shanghai Yaxin Biotechnology Co., Ltd. has the ability to produce and supply high-purity and high-activity biological products, together with complete supervision services, making the company the preferred supplier of many leading international biopharmaceutical companies.